Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation

Autoimmune diseases develop in approximately 5% of humans. They can arise when self-tolerance checkpoints of the immune system are bypassed as a consequence of inherited mutations of key genes involved in lymphocyte activation, survival, or death. For example, autoimmune lymphoproliferative syndrome...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Magerus-Chatinet, Aude, Neven, Bénédicte, Stolzenberg, Marie-Claude, Daussy, Cécile, Arkwright, Peter D., Lanzarotti, Nina, Schaffner, Catherine, Cluet-Dennetiere, Sophie, Haerynck, Filomeen, Michel, Gérard, Bole-Feysot, Christine, Zarhrate, Mohammed, Radford-Weiss, Isabelle, Romana, Serge P., Picard, Capucine, Fischer, Alain, Rieux-Laucat, Frédéric
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007148/
https://ncbi.nlm.nih.gov/pubmed/21183795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43752
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker