Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice

It was recently demonstrated in mice that knockout of the flavin-containing monooxygenase 5 gene, Fmo5, slows metabolic ageing via pleiotropic effects. We have now used an NMR-based metabonomics approach to study the effects of ageing directly on the metabolic profiles of urine and plasma from male,...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Varshavi, Dorsa, Scott, Flora H., Varshavi, Dorna, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A., Everett, Jeremy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900034/
https://ncbi.nlm.nih.gov/pubmed/29686991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00028
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