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How multi-scale structural biology elucidated context-dependent variability in ectodomain conformation along with the ligand capture and release cycle for LDLR family members

The low-density lipoprotein receptor (LDLR) and its homologs capture and internalize lipoproteins into the cell. Due to the fact that LDLR family members possess a modular ectodomain that undergoes dynamic conformational changes, multi-scale structural analysis has been performed so as to understand...

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Detalhes bibliográficos
Publicado no:Biophys Rev
Autor principal: Nogi, Terukazu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899722/
https://ncbi.nlm.nih.gov/pubmed/29204877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-017-0362-7
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