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Crystal structure of human lysyl oxidase-like 2 (hLOXL2) in a precursor state

Lysyl oxidases (LOXs), a type of copper- and lysyl tyrosylquinone (LTQ) -dependent amine oxidase, catalyze the oxidative deamination of lysine residues of extracellular matrix (ECM) proteins such as elastins and collagens and generate aldehyde groups. The oxidative deamination of lysine represents t...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Zhang, Xi, Wang, Qifan, Wu, Jianping, Wang, Jiawei, Shi, Yigong, Liu, Minhao
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899467/
https://ncbi.nlm.nih.gov/pubmed/29581294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720859115
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