Correlation of plasma concentration and adverse effects of bosutinib: standard dose or dose-escalation regimens of bosutinib treatment for patients with chronic myeloid leukemia

PURPOSE: To investigate the exposure-toxicity relationship of bosutinib and to identify the target trough plasma concentration (C(0)). METHODS: The toxicity and C(0) of bosutinib in Japanese chronic myeloid leukemia (CML) patients were monitored every 2 weeks for the first 3 months of treatment, and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Exp Hematol Oncol
Main Authors: Mita, Akiko, Abumiya, Maiko, Miura, Masatomo, Niioka, Takenori, Takahashi, Saori, Yoshioka, Tomoko, Kameoka, Yoshihiro, Takahashi, Naoto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899348/
https://ncbi.nlm.nih.gov/pubmed/29682402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-018-0101-1
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados