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Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis

Muscle atrophy with weakness is a core feature of amyotrophic lateral sclerosis (ALS) that has long been attributed to motor neuron loss alone. However, several studies in ALS patients, and more so in animal models, have challenged this assumption with the latter providing direct evidence that muscl...

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Podrobná bibliografie
Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Cykowski, Matthew D., Powell, Suzanne Z., Appel, Joan W., Arumanayagam, Anithachristy S., Rivera, Andreana L., Appel, Stanley H.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899326/
https://ncbi.nlm.nih.gov/pubmed/29653597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0528-y
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