Loading...
Intracerebroventricular Administration of a 2′-O-Methyl Phosphorothioate Antisense Oligonucleotide Results in Activation of the Innate Immune System in Mouse Brain
Antisense oligonucleotides (AONs) are versatile molecules that can be used to modulate gene expression by binding to RNA. The therapeutic potential of AONs appears particularly high in the central nervous system, due to excellent distribution and uptake in brain cells, as well as good tolerability i...
Na minha lista:
| Udgivet i: | Nucleic Acid Ther |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Mary Ann Liebert, Inc.
2018
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899290/ https://ncbi.nlm.nih.gov/pubmed/29565739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2017.0705 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|