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Loss of caveolin-3-dependent regulation of I(Ca) in rat ventricular myocytes in heart failure

β(2)-Adrenoceptors and L-type Ca(2+) current (I(Ca)) redistribute from the t-tubules to the surface membrane of ventricular myocytes from failing hearts. The present study investigated the role of changes in caveolin-3 and PKA signaling, both of which have previously been implicated in this redistri...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Heart Circ Physiol
Prif Awduron: Bryant, Simon M., Kong, Cherrie H. T., Cannell, Mark B., Orchard, Clive H., James, Andrew F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899261/
https://ncbi.nlm.nih.gov/pubmed/29101175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00458.2017
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