The Effects of Aging on the Regulation of T-Tubular I(Ca) by Caveolin in Mouse Ventricular Myocytes

Aging is associated with diminished cardiac function in males. Cardiac excitation-contraction coupling in ventricular myocytes involves Ca influx via the Ca current (I(Ca)) and Ca release from the sarcoplasmic reticulum, which occur predominantly at t-tubules. Caveolin-3 regulates t-tubular I(Ca), p...

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Bibliographic Details
Published in:J Gerontol A Biol Sci Med Sci
Main Authors: Kong, Cherrie H T, Bryant, Simon M, Watson, Judy J, Gadeberg, Hanne C, Roth, David M, Patel, Hemal H, Cannell, Mark B, Orchard, Clive H, James, Andrew F
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
The Journal of Gerontology: Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946816/
https://ncbi.nlm.nih.gov/pubmed/29236992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glx242
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