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Altered distribution of I(Ca) impairs Ca release at the t-tubules of ventricular myocytes from failing hearts
In mammalian cardiac ventricular myocytes, Ca influx and release occur predominantly at t-tubules, ensuring synchronous Ca release throughout the cell. Heart failure is associated with disrupted t-tubule structure, but its effect on t-tubule function is less clear. We therefore investigated Ca influ...
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Publicado no: | J Mol Cell Cardiol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Academic Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564288/ https://ncbi.nlm.nih.gov/pubmed/26103619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.06.012 |
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