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Cholesterol depletion does not alter the capacitance or Ca handling of the surface or t‐tubule membranes in mouse ventricular myocytes

Cholesterol is a key component of the cell plasma membrane. It has been suggested that the t‐tubule membrane of cardiac ventricular myocytes is enriched in cholesterol and that this plays a role in determining t‐tubule structure and function. We have used methyl‐β‐cyclodextrin (Mβ CD) to deplete cho...

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Dettagli Bibliografici
Pubblicato in:Physiol Rep
Autori principali: Gadeberg, Hanne C., Kong, Cherrie H. T., Bryant, Simon M., James, Andrew F., Orchard, Clive H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704078/
https://ncbi.nlm.nih.gov/pubmed/29150591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13500
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