Pretreatment rate of decay in forced vital capacity predicts long-term response to pirfenidone in patients with idiopathic pulmonary fibrosis

Pirfenidone reduces functional decline in patients with Idiopathic Pulmonary Fibrosis (IPF). However, response to treatment is highly heterogeneous. We sought to evaluate whether response to pirfenidone is influenced by the pretreatment rate of forced vital capacity (FVC) decline. Fifty-six IPF pati...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Biondini, Davide, Balestro, Elisabetta, Lacedonia, Donato, Cerri, Stefania, Milaneschi, Rosanna, Luppi, Fabrizio, Cocconcelli, Elisabetta, Bazzan, Erica, Clini, Enrico, Foschino Barbaro, Maria Pia, Gregori, Dario, Cosio, Manuel G, Saetta, Marina, Spagnolo, Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899162/
https://ncbi.nlm.nih.gov/pubmed/29654244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24303-4
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