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Photoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3)

For many neurodegenerative disorders, expression of a pathological protein by one cell type impedes function of other cell types, which in turn contributes to the death of the first cell type. In transgenic mice modelling Stargardt-like (STGD3) maculopathy, human mutant ELOVL4 expression by photorec...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Dejos, Camille, Kuny, Sharee, Han, Woo Hyun, Capel, Heather, Lemieux, Hélène, Sauvé, Yves
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899129/
https://ncbi.nlm.nih.gov/pubmed/29654292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24357-4
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