Photoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3)

For many neurodegenerative disorders, expression of a pathological protein by one cell type impedes function of other cell types, which in turn contributes to the death of the first cell type. In transgenic mice modelling Stargardt-like (STGD3) maculopathy, human mutant ELOVL4 expression by photorec...

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Published in:Sci Rep
Main Authors: Dejos, Camille, Kuny, Sharee, Han, Woo Hyun, Capel, Heather, Lemieux, Hélène, Sauvé, Yves
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899129/
https://ncbi.nlm.nih.gov/pubmed/29654292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24357-4
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