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What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination?: Is Affinity Maturation a Self-Defeating Process for Eliciting Broad Protection?

Vaccinations are one of the greatest success stories of modern medicine, saving millions of lives since their widespread adoption. However, several diseases continue to elude highly effective vaccination strategies. Chief among these are human immunodeficiency virus (HIV) and influenza (flu), both o...

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Detaylı Bibliyografya
Yayımlandı:Cold Spring Harb Perspect Biol
Asıl Yazarlar: Stamper, Christopher T., Wilson, Patrick C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899041/
https://ncbi.nlm.nih.gov/pubmed/28630076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a028803
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