Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation

RATIONALE: Cardiac fibrosis plays a critical role in the pathogenesis of heart failure (HF). Excessive accumulation of extracellular matrix (ECM) resulting from cardiac fibrosis impairs cardiac contractile function and increases arrhythmogenicity. Current treatment options for cardiac fibrosis, howe...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Circ Res
Egile Nagusiak: Shih, Ying-Chun, Chen, Chao-Ling, Zhang, Yan, Mellor, Rebecca L., Kanter, Evelyn M., Fang, Yun, Wang, Hua-Chi, Hung, Chen-Ting, Nong, Jing-Yi, Chen, Hui-Ju, Lee, Tzu-Han, Tseng, Yi-Shuan, Chen, Chiung-Nien, Wu, Chau-Chung, Lin, Shuei-Liong, Yamada, Kathryn A., Nerbonne, Jeanne M., Yang, Kai-Chien
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899016/
https://ncbi.nlm.nih.gov/pubmed/29535165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312130
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