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A novel missense mutation in HSF4 causes autosomal-dominant congenital lamellar cataract in a British family

PURPOSE: Inherited cataract, opacification of the lens, is the most common worldwide cause of blindness in children. We aimed to identify the genetic cause of isolated autosomal-dominant lamellar cataract in a five-generation British family. METHODS: Whole exome sequencing (WES) was performed on two...

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Bibliografski detalji
Izdano u:Eye (Lond)
Glavni autori: Berry, V, Pontikos, N, Moore, A, Ionides, A C W, Plagnol, V, Cheetham, M E, Michaelides, M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2018
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898855/
https://ncbi.nlm.nih.gov/pubmed/29243736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/eye.2017.268
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