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Transethosomal gels as carriers for the transdermal delivery of colchicine: statistical optimization, characterization, and ex vivo evaluation
INTRODUCTION: Colchicine is used for the treatment of gout, pseudo-gout, familial Mediterranean fever, and many other illnesses. Its oral administration is associated with poor bioavailability and severe gastrointestinal side effects. The drug is also known to have a low therapeutic index. Thus to o...
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| Pubblicato in: | Drug Des Devel Ther |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5898596/ https://ncbi.nlm.nih.gov/pubmed/29670336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S158018 |
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