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Connexin hemichannels mediate glutathione transport and protect lens fiber cells from oxidative stress

Elevated oxidized stress contributes to lens cataracts, and gap junctions play important roles in maintaining lens transparency. As well as forming gap junctions, connexin (Cx) proteins also form hemichannels. Here, we report a new mechanism whereby hemichannels mediate transport of reductant glutat...

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Foilsithe in:J Cell Sci
Main Authors: Shi, Wen, Riquelme, Manuel A., Gu, Sumin, Jiang, Jean X.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Company of Biologists Ltd 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897712/
https://ncbi.nlm.nih.gov/pubmed/29487175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.212506
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