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Connexin hemichannels mediate glutathione transport and protect lens fiber cells from oxidative stress
Elevated oxidized stress contributes to lens cataracts, and gap junctions play important roles in maintaining lens transparency. As well as forming gap junctions, connexin (Cx) proteins also form hemichannels. Here, we report a new mechanism whereby hemichannels mediate transport of reductant glutat...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897712/ https://ncbi.nlm.nih.gov/pubmed/29487175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.212506 |
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