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Connexin hemichannels mediate glutathione transport and protect lens fiber cells from oxidative stress

Elevated oxidized stress contributes to lens cataracts, and gap junctions play important roles in maintaining lens transparency. As well as forming gap junctions, connexin (Cx) proteins also form hemichannels. Here, we report a new mechanism whereby hemichannels mediate transport of reductant glutat...

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Detalles Bibliográficos
Publicado en:J Cell Sci
Main Authors: Shi, Wen, Riquelme, Manuel A., Gu, Sumin, Jiang, Jean X.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897712/
https://ncbi.nlm.nih.gov/pubmed/29487175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.212506
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