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Connexin hemichannels mediate glutathione transport and protect lens fiber cells from oxidative stress
Elevated oxidized stress contributes to lens cataracts, and gap junctions play important roles in maintaining lens transparency. As well as forming gap junctions, connexin (Cx) proteins also form hemichannels. Here, we report a new mechanism whereby hemichannels mediate transport of reductant glutat...
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Vydáno v: | J Cell Sci |
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Hlavní autoři: | , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
The Company of Biologists Ltd
2018
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897712/ https://ncbi.nlm.nih.gov/pubmed/29487175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.212506 |
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