Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG proteins in the heart

Reduced levels of the cardiac human (h)ERG ion channel protein and the corresponding repolarizing current I(Kr) can cause arrhythmia and sudden cardiac death, but the underlying cellular mechanisms controlling hERG surface expression are not well understood. Here, we identified TRIOBP-1, an F-actin-...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Jones, David K., Johnson, Ashley C., Roti Roti, Elon C., Liu, Fang, Uelmen, Rebecca, Ayers, Rebecca A., Baczko, Istvan, Tester, David J., Ackerman, Michael J., Trudeau, Matthew C., Robertson, Gail A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897710/
https://ncbi.nlm.nih.gov/pubmed/29507111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.206730
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