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Polycystin 1 loss of function is directly linked to an imbalance in G-protein signaling in the kidney
The development of the kidney relies on the establishment and maintenance of a precise tubular diameter of its functional units, the nephrons. This process is disrupted in polycystic kidney disease (PKD), resulting in dilations of the nephron and renal cyst formation. In the course of exploring G-pr...
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| Udgivet i: | Development |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Company of Biologists Ltd
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897598/ https://ncbi.nlm.nih.gov/pubmed/29530879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.158931 |
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