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The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity

The RNA-binding protein Bicaudal C is an important regulator of embryonic development in C. elegans, Drosophila and Xenopus. In mouse, bicaudal C (Bicc1) mutants are characterized by the formation of fluid-filled cysts in the kidney and by expansion of epithelial ducts in liver and pancreas. This ph...

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Autors principals: Tran, Uyen, Zakin, Lise, Schweickert, Axel, Agrawal, Raman, Döger, Remziye, Blum, Martin, De Robertis, E. M., Wessely, Oliver
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835326/
https://ncbi.nlm.nih.gov/pubmed/20215348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.046045
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