Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice

Mutations in mitochondrial DNA (mtDNA) lead to heteroplasmy, i.e., the intracellular coexistence of wild-type and mutant mtDNA strands, which impact a wide spectrum of diseases but also physiological processes, including endurance exercise performance in athletes. However, the phenotypic consequence...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Hirose, Misa, Schilf, Paul, Gupta, Yask, Zarse, Kim, Künstner, Axel, Fähnrich, Anke, Busch, Hauke, Yin, Junping, Wright, Marvin N., Ziegler, Andreas, Vallier, Marie, Belheouane, Meriem, Baines, John F, Tautz, Diethard, Johann, Kornelia, Oelkrug, Rebecca, Mittag, Jens, Lehnert, Hendrik, Othman, Alaa, Jöhren, Olaf, Schwaninger, Markus, Prehn, Cornelia, Adamski, Jerzy, Shima, Kensuke, Rupp, Jan, Häsler, Robert, Fuellen, Georg, Köhling, Rüdiger, Ristow, Michael, Ibrahim, Saleh M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897405/
https://ncbi.nlm.nih.gov/pubmed/29651131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24290-6
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak