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Meta-populational demes constitute a reservoir for large MHC allele diversity in wild house mice (Mus musculus)

BACKGROUND: The MHC class I and II loci mediate the adaptive immune response and belong to the most polymorphic loci in vertebrate genomes. In fact, the number of different alleles in a given species is often so large that it remains a challenge to provide an evolutionary model that can fully accoun...

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Publicado en:Front Zool
Autores principales: Linnenbrink, Miriam, Teschke, Meike, Montero, Inka, Vallier, Marie, Tautz, Diethard
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910556/
https://ncbi.nlm.nih.gov/pubmed/29721030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12983-018-0266-9
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