Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans

The formation of the vertebrate brain requires the generation, migration, differentiation and survival of neurons. Genetic mutations that perturb these critical cellular events can result in malformations of the telencephalon, providing a molecular window into brain development. Here we report the i...

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Publicat a:Nat Neurosci
Autors principals: Gstrein, Thomas, Edwards, Andrew, Přistoupilová, Anna, Leca, Ines, Breuss, Martin, Pilat-Carotta, Sandra, Hansen, Andi H., Tripathy, Ratna, Traunbauer, Anna K., Hochstoeger, Tobias, Rosoklija, Gavril, Repic, Marco, Landler, Lukas, Stránecký, Viktor, Dürnberger, Gerhard, Keane, Thomas M., Zuber, Johannes, Adams, David J., Flint, Jonathan, Honzik, Tomas, Gut, Marta, Beltran, Sergi, Mechtler, Karl, Sherr, Elliott, Kmoch, Stanislav, Gut, Ivo, Keays, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897053/
https://ncbi.nlm.nih.gov/pubmed/29311744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-017-0053-5
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