A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse

Microtubules play a critical role in multiple aspects of neurodevelopment, including the generation, migration and differentiation of neurons. A recurrent mutation (R402H) in the α-tubulin gene TUBA1A is known to cause lissencephaly with cerebellar and striatal phenotypes. Previous work has shown th...

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Bibliografski detalji
Izdano u:PLoS Genet
Glavni autori: Leca, Ines, Phillips, Alexander William, Hofer, Iris, Landler, Lukas, Ushakova, Lyubov, Cushion, Thomas David, Dürnberger, Gerhard, Stejskal, Karel, Mechtler, Karl, Keays, David Anthony
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660477/
https://ncbi.nlm.nih.gov/pubmed/33137126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009104
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