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Mutation of the α-tubulin Tuba1a leads to straighter microtubules and perturbs neuronal migration
Brain development involves extensive migration of neurons. Microtubules (MTs) are key cellular effectors of neuronal displacement that are assembled from α/β-tubulin heterodimers. Mutation of the α-tubulin isotype TUBA1A is associated with cortical malformations in humans. In this study, we provide...
Gespeichert in:
| Veröffentlicht in: | J Cell Biol |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551700/ https://ncbi.nlm.nih.gov/pubmed/28687665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201607074 |
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