TERRA and the histone methyltransferase Dot1 cooperate to regulate senescence in budding yeast

The events underlying senescence induced by critical telomere shortening are not fully understood. Here we provide evidence that TERRA, a non-coding RNA transcribed from subtelomeres, contributes to senescence in yeast lacking telomerase (tlc1Δ). Levels of TERRA expressed from multiple telomere ends...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wanat, Jennifer J., Logsdon, Glennis A., Driskill, Jordan H., Deng, Zhong, Lieberman, Paul M., Johnson, F. Brad
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896980/
https://ncbi.nlm.nih.gov/pubmed/29649255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195698
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker