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A futile battle? Protein quality control and the stress of aging

There exists a phenomenon in aging research whereby early life stress can have positive impacts on longevity. The mechanisms underlying these observations suggest a robust, long-lasting induction of cellular defense mechanisms. These include the various unfolded protein responses of the ER, cytosol,...

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Bibliografiske detaljer
Udgivet i:Dev Cell
Main Authors: Higuchi-Sanabria, Ryo, Frankino, Phillip Andrew, Paul, Joseph West, Tronnes, Sarah Uhlein, Dillin, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896312/
https://ncbi.nlm.nih.gov/pubmed/29401418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.12.020
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