UPR(ER) promotes lipophagy independent of chaperones to extend life span

Longevity is dictated by a combination of environmental and genetic factors. One of the key mechanisms to regulate life-span extension is the induction of protein chaperones for protein homeostasis. Ectopic activation of the unfolded protein response of the endoplasmic reticulum (UPR(ER)) specifical...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Adv
Autori principali: Daniele, Joseph R., Higuchi-Sanabria, Ryo, Durieux, Jenni, Monshietehadi, Samira, Ramachandran, Vidhya, Tronnes, Sarah U., Kelet, Naame, Sanchez, Melissa, Metcalf, Melissa G., Garcia, Gilberto, Frankino, Phillip A., Benitez, Camila, Zeng, Mandy, Esping, Daniel J., Joe, Larry, Dillin, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938708/
https://ncbi.nlm.nih.gov/pubmed/31911951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz1441
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi