X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation

Mechanisms establishing higher-order chromosome structures and their roles in gene regulation are elusive. We analyzed chromosome architecture during nematode X-chromosome dosage compensation, which represses transcription via a dosage-compensation condensin complex (DCC) that binds hermaphrodite Xs...

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發表在:Dev Cell
Main Authors: Anderson, Erika C., Frankino, Phillip A., Higuchi-Sanabria, Ryo, Yang, Qiming, Bian, Qian, Podshivalova, Katie, Shin, Aram, Kenyon, Cynthia, Dillin, Andrew, Meyer, Barbara J.
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6810858/
https://ncbi.nlm.nih.gov/pubmed/31495695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.08.004
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