The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils

Transmissible cancers are clonal lineages that spread through populations via contagious cancer cells. Although rare in nature, two facial tumor clones affect Tasmanian devils. Here we perform comparative genetic and functional characterization of these lineages. The two cancers have similar pattern...

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Publié dans:Cancer Cell
Auteurs principaux: Stammnitz, Maximilian R., Coorens, Tim H.H., Gori, Kevin C., Hayes, Dane, Fu, Beiyuan, Wang, Jinhong, Martin-Herranz, Daniel E., Alexandrov, Ludmil B., Baez-Ortega, Adrian, Barthorpe, Syd, Beck, Alexandra, Giordano, Francesca, Knowles, Graeme W., Kwon, Young Mi, Hall, George, Price, Stacey, Pye, Ruth J., Tubio, Jose M.C., Siddle, Hannah V.T., Sohal, Sukhwinder Singh, Woods, Gregory M., McDermott, Ultan, Yang, Fengtang, Garnett, Mathew J., Ning, Zemin, Murchison, Elizabeth P.
Format: Artigo
Langue:Inglês
Publié: Cell Press 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896245/
https://ncbi.nlm.nih.gov/pubmed/29634948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.03.013
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