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Bexarotene inhibits the viability of non-small cell lung cancer cells via slc10a2/PPARγ/PTEN/mTOR signaling pathway

BACKGROUND: Thirty to 40 % of non-small cell lung cancer (NSCLC) patients developed higher hypertriglyceridemia in the process of treatment with bexarotene. And bioinformatics studies discovered that the expression of slc10a2 was increased in high-grade hypertriglyceridemia patients. So, we will exp...

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Pubblicato in:BMC Cancer
Autori principali: Ai, Xinghao, Mao, Feng, Shen, Shengping, Shentu, Yang, Wang, Jiejun, Lu, Shun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896077/
https://ncbi.nlm.nih.gov/pubmed/29642873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4224-x
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