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A two-tiered unsupervised clustering approach for drug repositioning through heterogeneous data integration

BACKGROUND: Drug repositioning is the process of identifying new uses for existing drugs. Computational drug repositioning methods can reduce the time, costs and risks of drug development by automating the analysis of the relationships in pharmacology networks. Pharmacology networks are large and he...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Hameed, Pathima Nusrath, Verspoor, Karin, Kusljic, Snezana, Halgamuge, Saman
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896044/
https://ncbi.nlm.nih.gov/pubmed/29642848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2123-4
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