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Computational drug repositioning through heterogeneous network clustering

BACKGROUND: Given the costly and time consuming process and high attrition rates in drug discovery and development, drug repositioning or drug repurposing is considered as a viable strategy both to replenish the drying out drug pipelines and to surmount the innovation gap. Although there is a growin...

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Detalhes bibliográficos
Main Authors: Wu, Chao, Gudivada, Ranga C, Aronow, Bruce J, Jegga, Anil G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029299/
https://ncbi.nlm.nih.gov/pubmed/24564976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-S5-S6
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