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A physarum-inspired prize-collecting steiner tree approach to identify subnetworks for drug repositioning
BACKGROUND: Drug repositioning can reduce the time, costs and risks of drug development by identifying new therapeutic effects for known drugs. It is challenging to reposition drugs as pharmacological data is large and complex. Subnetwork identification has already been used to simplify the visualiz...
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| Publicado no: | BMC Syst Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5249043/ https://ncbi.nlm.nih.gov/pubmed/28105946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0371-3 |
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