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A physarum-inspired prize-collecting steiner tree approach to identify subnetworks for drug repositioning
BACKGROUND: Drug repositioning can reduce the time, costs and risks of drug development by identifying new therapeutic effects for known drugs. It is challenging to reposition drugs as pharmacological data is large and complex. Subnetwork identification has already been used to simplify the visualiz...
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| Publicat a: | BMC Syst Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5249043/ https://ncbi.nlm.nih.gov/pubmed/28105946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0371-3 |
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