Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through Fgf4/Fgfr2 signaling in preimplantation mouse embryos

Oct4 and Sox2 regulate the expression of target genes such as Nanog, Fgf4, and Utf1, by binding to their respective regulatory motifs. Their functional cooperation is reflected in their ability to heterodimerize on adjacent cis regulatory motifs, the composite Sox/Oct motif. Given that Oct4 and Sox2...

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Detaylı Bibliyografya
Yayımlandı:Biochem J
Asıl Yazarlar: Mistri, Tapan Kumar, Arindrarto, Wibowo, Ng, Wei Ping, Wang, Choayang, Lim, Leng Hiong, Sun, Lili, Chambers, Ian, Wohland, Thorsten, Robson, Paul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896025/
https://ncbi.nlm.nih.gov/pubmed/29487166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170418
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