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Peripherally Administered Y(2)-Receptor Antagonist BIIE0246 Prevents Diet-Induced Obesity in Mice With Excess Neuropeptide Y, but Enhances Obesity in Control Mice
Neuropeptide Y (NPY) plays an important role in the regulation of energy homeostasis in the level of central and sympathetic nervous systems (SNSs). Genetic silencing of peripheral Y(2)-receptors have anti-obesity effects, but it is not known whether pharmacological blocking of peripheral Y(2)-recep...
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| Publicado no: | Front Pharmacol |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5895854/ https://ncbi.nlm.nih.gov/pubmed/29674968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00319 |
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