Neuropeptide Y Overexpressing Female and Male Mice Show Divergent Metabolic but Not Gut Microbial Responses to Prenatal Metformin Exposure

BACKGROUND: Prenatal metformin exposure has been shown to improve the metabolic outcome in the offspring of high fat diet fed dams. However, if this is evident also in a genetic model of obesity and whether gut microbiota has a role, is not known. METHODS: The metabolic effects of prenatal metformin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Salomäki-Myftari, Henriikka, Vähätalo, Laura H., Ailanen, Liisa, Pietilä, Sami, Laiho, Asta, Hänninen, Arno, Pursiheimo, Juha-Pekka, Munukka, Eveliina, Rintala, Anniina, Savontaus, Eriika, Pesonen, Ullamari, Koulu, Markku
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5040270/
https://ncbi.nlm.nih.gov/pubmed/27681875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163805
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