Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis

In infants intolerant of enteral feeding because of intestinal disease, parenteral nutrition may be associated with cholestasis, which can progress to end-stage liver disease. Here we show the function of hepatic macrophages and phytosterols in parenteral nutrition-associated cholestasis (PNAC) path...

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Publicado no:Nat Commun
Main Authors: El Kasmi, Karim C., Vue, Padade M., Anderson, Aimee L., Devereaux, Michael W., Ghosh, Swati, Balasubramaniyan, Natarajan, Fillon, Sophie A., Dahrenmoeller, Carola, Allawzi, Ayed, Woods, Crystal, McKenna, Sarah, Wright, Clyde J., Johnson, Linda, D’Alessandro, Angelo, Reisz, Julie A., Nozik-Grayck, Eva, Suchy, Frederick J., Sokol, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895696/
https://ncbi.nlm.nih.gov/pubmed/29643332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03764-1
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