Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis

In infants intolerant of enteral feeding because of intestinal disease, parenteral nutrition may be associated with cholestasis, which can progress to end-stage liver disease. Here we show the function of hepatic macrophages and phytosterols in parenteral nutrition-associated cholestasis (PNAC) path...

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Udgivet i:Nat Commun
Main Authors: El Kasmi, Karim C., Vue, Padade M., Anderson, Aimee L., Devereaux, Michael W., Ghosh, Swati, Balasubramaniyan, Natarajan, Fillon, Sophie A., Dahrenmoeller, Carola, Allawzi, Ayed, Woods, Crystal, McKenna, Sarah, Wright, Clyde J., Johnson, Linda, D’Alessandro, Angelo, Reisz, Julie A., Nozik-Grayck, Eva, Suchy, Frederick J., Sokol, Ronald J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895696/
https://ncbi.nlm.nih.gov/pubmed/29643332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03764-1
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