Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung

Clinical studies have demonstrated a strong association between both acute toxic exposure and the repetitive, chronic exposure to acetaminophen (APAP) with pulmonary dysfunction. However, the mechanisms underlying this association are unknown. Preclinical reports have demonstrated that significant b...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Sandoval, Jeryl, Orlicky, David J., Allawzi, Ayed, Butler, Brittany, Ju, Cynthia, Phan, Caroline T., Toston, Roy, De Dios, Robyn, Nguyen, Leanna, McKenna, Sarah, Nozik-Grayck, Eva, Wright, Clyde J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914885/
https://ncbi.nlm.nih.gov/pubmed/31885815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7595126
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