HEx: A heterologous expression platform for the discovery of fungal natural products

For decades, fungi have been a source of U.S. Food and Drug Administration–approved natural products such as penicillin, cyclosporine, and the statins. Recent breakthroughs in DNA sequencing suggest that millions of fungal species exist on Earth, with each genome encoding pathways capable of generat...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Harvey, Colin J. B., Tang, Mancheng, Schlecht, Ulrich, Horecka, Joe, Fischer, Curt R., Lin, Hsiao-Ching, Li, Jian, Naughton, Brian, Cherry, James, Miranda, Molly, Li, Yong Fuga, Chu, Angela M., Hennessy, James R., Vandova, Gergana A., Inglis, Diane, Aiyar, Raeka S., Steinmetz, Lars M., Davis, Ronald W., Medema, Marnix H., Sattely, Elizabeth, Khosla, Chaitan, St. Onge, Robert P., Tang, Yi, Hillenmeyer, Maureen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895447/
https://ncbi.nlm.nih.gov/pubmed/29651464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aar5459
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