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Evolution of chemical diversity by coordinated gene swaps in type II polyketide gene clusters
Natural product biosynthetic pathways generate molecules of enormous structural complexity and exquisitely tuned biological activities. Studies of natural products have led to the discovery of many pharmaceutical agents, particularly antibiotics. Attempts to harness the catalytic prowess of biosynth...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4653136/ https://ncbi.nlm.nih.gov/pubmed/26499248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511688112 |
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