Fasudil improves endothelial dysfunction in rats exposed to chronic intermittent hypoxia through RhoA/ROCK/NFATc3 pathway

Endothelial dysfunction is one of the main pathological changes in Obstructive sleep apnoea (OSA). The Rho kinase (ROCK) pathway is associated with endothelial dysfunction. However, the interaction between ROCK and nuclear factor of activated T cells isoform c3 (NFATc3) in the development of this pa...

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Udgivet i:PLoS One
Main Authors: Li, Jie-Ru, Zhao, Ya-Shuo, Chang, Yue, Yang, Sheng-Chang, Guo, Ya-Jing, Ji, En-Sheng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895022/
https://ncbi.nlm.nih.gov/pubmed/29641598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195604
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