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Fasudil improves endothelial dysfunction in rats exposed to chronic intermittent hypoxia through RhoA/ROCK/NFATc3 pathway

Endothelial dysfunction is one of the main pathological changes in Obstructive sleep apnoea (OSA). The Rho kinase (ROCK) pathway is associated with endothelial dysfunction. However, the interaction between ROCK and nuclear factor of activated T cells isoform c3 (NFATc3) in the development of this pa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Jie-Ru, Zhao, Ya-Shuo, Chang, Yue, Yang, Sheng-Chang, Guo, Ya-Jing, Ji, En-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895022/
https://ncbi.nlm.nih.gov/pubmed/29641598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0195604
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