Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease

Gene-based tests to study the combined effect of rare variants on a particular phenotype have been widely developed for case-control studies, but their evolution and adaptation for family-based studies, especially studies of complex incomplete families, has been slower. In this study, we have perfor...

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Vydáno v:Front Neurosci
Hlavní autoři: Fernández, Maria V., Budde, John, Del-Aguila, Jorge L., Ibañez, Laura, Deming, Yuetiva, Harari, Oscar, Norton, Joanne, Morris, John C., Goate, Alison M., Cruchaga, Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893779/
https://ncbi.nlm.nih.gov/pubmed/29670507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00209
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